Description

Metphage 500mg Tablet: An Overview
Introduction Metphage 500mg Tablet is a medication primarily used to manage type 2 diabetes mellitus. It contains metformin hydrochloride, which belongs to the class of drugs known as biguanides.
Composition The active ingredient in Metphage 500mg Tablet is metformin hydrochloride. This compound helps in controlling blood sugar levels in patients with type 2 diabetes.
Uses
Type 2 Diabetes Mellitus: Metphage 500mg Tablet is used as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Polycystic Ovary Syndrome (PCOS): It is also used off-label to manage symptoms of PCOS, particularly in improving insulin sensitivity.
Mechanism of Action Metformin works by:
Reducing hepatic glucose production.
Decreasing intestinal absorption of glucose.
Enhancing insulin sensitivity by increasing peripheral glucose uptake and utilization.
Dosage and Administration The typical starting dose for adults is 500 mg taken once or twice daily with meals. The dosage may be gradually increased based on the patient’s response and tolerance, with a maximum daily dose of 2550 mg.
Side Effects Common side effects include:
Gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal discomfort.
Metallic taste in the mouth.
Rare but serious side effects can include lactic acidosis, a condition characterized by the buildup of lactic acid in the blood, which requires immediate medical attention.
Precautions
Kidney Function: Regular monitoring of kidney function is essential, as metformin is contraindicated in patients with severe renal impairment.
Alcohol Consumption: Limit alcohol intake while taking Metphage, as it can increase the risk of lactic acidosis.
Other Medications: Inform your healthcare provider about any other medications you are taking to avoid potential interactions.
Conclusion Metphage 500mg Tablet is an effective medication for managing type 2 diabetes and improving insulin sensitivity in PCOS. Understanding its uses, mechanism of action, and potential side effects can help patients use this medication safely and effectively. Always consult with a healthcare professional before starting any new medication.