Vonoprazan is a proton pump inhibitor (PPI) used in adults to reduce stomach acid. This medication is primarily prescribed to promote the healing of erosive esophagitis, which is damage to the esophagus caused by stomach acid. Additionally, vonoprazan is used in combination with antibiotics to treat infections caused by Helicobacter pylori (H. pylori). Common side effects include an altered sense of taste, vaginal itching or discharge, bloating, indigestion, diarrhea, stomach pain, It is important to seek medical attention if you experience severe side effects.